General Information

  • ID:  hor002926
  • Uniprot ID:  P86554
  • Protein name:  Allatotropin-related peptide
  • Gene name:  NA
  • Organism:  Pentatoma rufipes (Forest bug) (Cimex rufipes)
  • Family:  NA
  • Source:  animal
  • Expression:  Expressed in the posterior region of the abdominal ventral nerve cord and in the fourth abdominal nerves (at protein level).
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Pentatoma (genus), Pentatominae (subfamily), Pentatomidae (family), Pentatomoidea (superfamily), Pentatomomorpha (infraorder), Panheteroptera, Neoheteroptera, Euheteroptera, Heteroptera (suborder), Prosorrhyncha, Hemiptera (order), Paraneoptera (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  GFKNVALSTARGF
  • Length:  13
  • Propeptide:  GFKNVALSTARGF
  • Signal peptide:  NA
  • Modification:  T13 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NO
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-O14604-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    AF-O14604-F1.pdbhor002926_AF2.pdbhor002926_ESM.pdb

Physical Information

Mass: 158179 Formula: C62H98N18O17
Absent amino acids: CDEHIMPQWY Common amino acids: AFG
pI: 11.65 Basic residues: 2
Polar residues: 5 Hydrophobic residues: 6
Hydrophobicity: 23.08 Boman Index: -1266
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 67.69
Instability Index: -886.15 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  19084564
  • Title:  Neuropeptides in Heteroptera: Identification of Allatotropin-Related Peptide and Tachykinin-Related Peptides Using MALDI-TOF Mass Spectrometry